Does anyone else have experience twitching between their thumb and forefinger. My recent bout started in my left calf - then moves into my left foot - then was in my right calf for a little. Well it amazingly has stopped in my left calf for the most part and is in the right thumb area. It is really jerking bad and as i work with a mouse all day and a computer its driving me nuts. I didnt mind the claves and foot too much cause if it started bugging me too much i would just stand up and walk a bit - walking for me always made the twitching stop only seemed to flare up when i was sitting and leegs relaxed. I dont know what to do to stop the thumb - its in one of the worst sopts - I started squeezing something really right when it bugs me too much - its seems to work ok cause it kinda tightens up the thumb muscle a bit which sems to help for some treason. I guess on the bright side if i keep squeezing things all day ill develop a huge fore arm. Anyone have any tip to help the thumb twitch - i wish it would go back to my calf!!