It has been quite a while since I've posted and not much has changed. Just putting my 2 cents in from a pharmacists point of few.... I know that a few people have felt that Benadryl has caused their twitches, but in all actuality is is probably the safest sleep aid there is out there. Ambien, Sonata, and the newest one Lunesta are very efficient, but do run the risk of becoming habit forming. Dramamine (diphenhydrinate) is just a slight tweak in the chemical form of Benadryl (diphenhydramine), but benadryl is the most commonly used OTC sleep aid (tylenol pm is benadryl and tylenol mixed). Tolerance can occur if you use it nightly for up to 4 weeks. Depending upon the person, another down side is how long it lasts in the body, which makes some people still feel groggy. Other possibility is Doxylamine which is another weak antihistamine, but has good sedation properties, It is in the product Unisom (Unisom also has a product with benadryl so read the box).