I wanted to come back to this and say that I had 6 of my "non-BFS" friends flick their thenar thumb muscle and 2 of them had the same reaction. One male, one female.Then, I took 15mg of Flexeril before bed last night. Besides sleeping like a baby, I felt NO twitches when I woke up, for a long time. AND the whole morning, I flicked my thumb thenar muscle, and it had NO reaction, zero twitches. Later on in the day, when my twitches started up again, I flicked my thenar muscle again, and there were the twitches again.So, for me, this tells me, when I am relaxed and my muscles are relaxed, the twitches (whether they are produced by flick or not) die down or totally go away.