YES!! I discovered i had an iron def, and i think it has been 'part' of the cause of my twitching. I just finished a second round of iron supplements ( 8 weeks in the fall and 6 weeks now) and with the second dose i have noticed a drastic difference in my twitching, i still twitch but not as often and it's not as intense. If you are taking iron supplements make sure you are monitered by a doctor, if the level of iron gets too high in the blood it can be DEADLY!!!!!