Chronic Twitching and Muscle Pain

So I won't rehash my entire story, but keeping things relatively short, I have been twitching non stop for essentially 10 weeks now (and before that, occasional twitching here and there for a few months). I find that my muscles have been getting sore all over and in particular, my right thigh has been bothering me for essentially this entire period. It is quite painful and becomes very painful if I have to stand for any significant length of time (although doesn't seem to bother me when I run - very weird). To make my anxiety worst, I have a small dent at the distal aspect of the R vastus lateralis, noticed especially when my knee is in flexion (i.e., sitting at a chair). The dent is noticeable and at least 6 x 6cm and about 2-3mm deep (not present on the left side). I hope it is from subcutaneous fat breakdown from crossing my legs over the years and with my extended running and leg toning, just really started to notice it now. To make matters worst, I measured the circumference of my right thigh yesterday at multiple points, and no matter where I seemed to measure from, it was 0.25 to 1.0 inches smaller (I do have very large legs FYI - I am 220lbs and 6'2). Needless to say, the fact that my thigh continues to hurt, 'feels' weak, has this dent, and is objectively smaller by tape measure (not noticeably smaller though) has me quite concerned. On the flip side, I tell myself I don't have clinical weakness, I had an EMG test that exact muscle only 2 weeks ago (it was clear...I had one sharp wave in my calf that the neuro said not to worry about and the rest of the EMG was fine except for fasiculations), and I continue to run. Could it be that I have simply caused a repetitive strain injury that I refuse to let heal? Running is a vicious circle for me - I need it for my anxiety but with 8 straight months of it, I wonder if I am hurting my body? I know my question has already been answered - but ALS starting in a big muscle like my thigh - rare rare rare right? Advice appreciated as always... :)
 
There are so many things in the post that PROVE you are fine.First off, everybody has differences in measurements from one limb to the next. My calves are 1/2 inch different, thighes are 3/4 inch. Secondly, we have little dents all over the place. Your dent is nothing! Let it go. We all have them. Trust me on this one.If you had a neuromuscular disease that was causing atrophy or weakness in your thigh, then your EMG would have lit up like the fourth of July! Without weakness, true weakness like you can't climb stairs, and given your clean EMG you have absolutely NO REASON to be worried about anything nasty. NONE. Period.-Matt
 

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