Hi,I am a caffeine addict also, and am easily 10 cups per day (and coke of the cola variety). You could just IV me with caffeine. What Gracely said in her first post is right. (How do you get to know so much misses) Caffeine does lots of things to your body. It promotes positive effects by activating pathways associated with motivational and motor responses in the brain. Our man Prof M de Carvalho showed caffeine reduced a measurement called the 'cortical silent period'. This sounds more complicated than it is. Basically it is just a physiological measurement , and if this cortical silent period is shorter than it should be ( as was seen after caffeine administration ), it can signal there is a thing called cortical hyperexcitability. So he showed caffeine could cause excitability of motor pathways, perhaps by stopping intra cortical inhibitory circuits (pathways)There is huge interest in sports science in caffeine as acute ingestion makes muscles work more effectively during certain exercises. Think it does this as it helps synthesis a substance called ATP ( energy molecules the body generates and uses for fuel). Anyway caffeine can generate this energy ATP even in muscles exercising with low oxygen levels running through them ( I.e. through exertion).The reason I am spouting all this stupid information is to highlight that caffine has effects on CNS, cortical hyperexcitability, and directly in muscles themselves.A lot of studies don't even use that much caffeine, so it is reasonable to extrapolate, tthat high users like ourselves are getting some of these effects.Does this however result in caffeine causing fasciculation. I just dont know. I do know there are studies saying it can exacerbate the situation. For example the article I previously posted about fasciculation anxiety syndromes in clinicians (yes it exists), anyway caffeine was identified as a stimulant, but not source of their twitches. Other studies suggest caffeine has no effect, but they tend to be questioneer based. A lot of fasciculation can't be felt so for a proper answer I feel the study should have included emg before and after caffeine (probably not in their budget).Personally I had 2 of my emgs close together about a month apart. One was in the morning and I didn't have any coffee as I was late out of bed......mad rush......very detailed, long emg, lots of muscles, showed presence of a few odd fasciculation potentials in various locations Other emg was done one evening, I had had loads of caffeine, buzzing amounts...including one while waiting.......fasciculation potentials were more numerous and widespread. I did think about this at the time, but may have just been coincidental.Good luck with your withdrawal, you are a stronger person than me. I would murder someone if I had to go a day without the stuff.HxPS am going to murder someone anyway as have to keep editing post. Trying to use one of kids tablet and every second word I write is interrupted by a stupid game called Talking Tom......talking tom needs fed, talking tom needs toilet, talking tom needs to play whack the mouse.......aaaaaahhhhhhh ..... so sorry if post muddled but can't hear myself think, or write , blame talking bloody tom xxx
)))