JCVanilla4125
Well-known member
You're friend is a neurologist and I'm not trying to dispute what he says, but BFS is peripheral nerve hyperexcitability and from what I've read has more to do with potassium channels in the peripheral nerves, not the anterior horn cells of the spinal cord (as is the case with ALS). I do agree that a viral infection is probably the trigger (or at least a trigger) and that genetic predisposition plays a role (probably a large role) in ALS. What happens after the triggering event (in BFS) is anyones guess but most think that there is an autoimmune component with antibody formation against the potassium channels.