Cipro absolutely can cause long-term fasciculation and other neurological issues. It is listed on the side effect profile for the drug and there are published papers on there link to peripheral neuropathy. Since this is how my bfs started, I spent an extreme amount of time researching adr's linked to FQ antibiotics and 100% believe them to be the cause for some people. Obviously they aren't responsible for all cases of BFS, but there is a strong link for some of us. Search the archives here and you will find multiple examples.BTW, I was rx'd cipro for a supposed urinary tract infection, which the cultures came back negative. Had a back ache with traces of blood in my urine, so the doc ordered cultures and sent me home with Cipro. A week of cipro later, and no infection, I get slammed with extreme muscle fatigue, fascics, muscle/joint pain and a myriad of other sxs. The stuff almost ruined my life, but like most other things, my body recovered over time. Take care,Gary