I thought I'd bump this thread up from nearly 2 years ago just to bring some more discussion to what I think is a worthwhile area. I asked my 2nd neuro about alcohol possibly playing a role in my symptoms (I was a daily drinker - and no small quantity, either). He said he has not seen research into that area, but could imagine a correlation. He advised me to cut down my alcohol consumption and see if anything changed. While I didn't really cut down right away, I did stop drinking entirely on Feburary 7 of this year (for a variety of reasons, muscle twitching being the absolute lowest on the totem pole). So I'm posting to share my results after having gone from a daily binge drinker of 10+ years to a Sober Susan for 6.5 months. Every area of my life has improved with sobriety - marriage, self-confidence, cognition, lost weight, etc - except BFS. Waking up hungover would cause my symptoms to be really intense for several hours, so that part is obviously gone now; but the condition overall persists. Calves have still been twitching constantly for over two years, twitches all over, general fatigue, perceived weakness, etc... the whole gambit of standard BFS symptoms, really.So I'm here to report that, having gone from one extreme to another with my alcohol consumption, there are no changes/improvements to report - aside from eliminating the temporary flare-ups that come with hangovers. Anyone else have any similar experiences?